منابع مشابه
Brain drain, meningeal lymphatics and neurlogical disorders
The central nervous system (CNS) was considered to be devoid of classical lymphatic drainage. We recently challenged that paradigm by demonstrating the presence of a lymphatic vasculature in the surrounding of the brain called the meninges. We demonstrated that lymphatic vessels, expressing hall the markers for lymphatic endothelial cells (LEC; i.e Lyve-1, Prox1, podoplanin, VEGFR3 and CCL21) a...
متن کاملMalignant primary meningeal tumors.
1) Out of 160 primary meningeal tumors surgically treated, 10 cases had histologically malignant tumors. Of them two cases of sarcoma and one case of meningioma with marked invasiveness were filed in malignant (sarcoma) group, and six cases of angioblastic meningioma of hemangiopericytoma type and one case of meningioma with partial invasiveness in semi malignant group. 2) Average duration of s...
متن کاملMeningeal carcinomatosis in solid tumors.
The involvement of the leptomeninges by metastatic tumors can be observed in solid tumors, in which case it is termed meningeal carcinomatosis (MC), and in lymphoproliferative malignant disease. It is more common in breast and lung cancer, as well as melanoma, with adenocarcinoma being the most frequent histological type. MC is usually a late event, with disseminated and progressive disease alr...
متن کاملBrain drain
Professor Emeritus, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, UK, [email protected] In this issue, three papers discuss the issue of the brain drain: of psychiatrists from Egypt and Nigeria, and of nurses from East Africa. They explore the complexities of professional migration and its impact on the health of populations in source and recipient countries; they a...
متن کاملHow Do Meningeal Lymphatic Vessels Drain the CNS?
The many interactions between the nervous and the immune systems, which are active in both physiological and pathological states, have recently become more clearly delineated with the discovery of a meningeal lymphatic system capable of carrying fluid, immune cells, and macromolecules from the central nervous system (CNS) to the draining deep cervical lymph nodes. However, the exact localizatio...
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ژورنال
عنوان ژورنال: Cell Research
سال: 2020
ISSN: 1001-0602,1748-7838
DOI: 10.1038/s41422-020-0286-9